Peimine
Cat. No.：YN482386
CAS No. ：23496-41-5
| 产品名称: | Peimine |
| CAS No.: | 23496-41-5 |
| Chemical Name: | (5α)-cevane-3β,6α,20-triol |
| Synonyms: | 贝母甲素; Verticine; Dihydroisoimperialine |
| 分子量: | 431.65 |
| 分子式: | C₂₇H₄₅NO₃ |
| SMILES: | [H][C@]12[C@]3([H])C[C@H](O)[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])C[C@]([H])1[C@]5([H])CN6C[C@@H](C)CC[C@]([H])6[C@@](C)(O)[C@]([H])5CC2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 贝母甲素(Peimine; Verticine)是一个具有很好抗炎症活性的天然化合物。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Wang, D., Zhu, J., Wang, S., et al.Antitussive, expectorant and anti-inflammatory alkaloids from Bulbus Fritillariae CirrhosaeFitoterapia82(8),1290-1294(2011)
Xu, J., Zhao, W., Pan, L., et al.Peimine, a main active ingredient of Fritillaria, exhibits anti-inflammatory and pain suppression properties at the cellular levelFitoterapia111,1-6(2016)
Kan, L., Zhao, W., Pan, L., et al.Peimine inhibits hERG potassium channels through the channel inactivation statesBiomed. Pharmacother.89,838-844(2017)
Tan, H., Zhang, G., Yang, X., et al.Peimine inhibits the growth and motility of prostate cancer cells and induces apoptosis by disruption of intracellular calcium homeostasis through Ca2+ /CaMKII/JNK pathwayJ. Cell. Biochem.121(1),81-92(2020)
Chen, K., Lv, Z.-T., Zhou, C.-H., et al.Peimine suppresses interleukin‑1β‑induced inflammation via MAPK downregulation in chondrocytesInt. J. Mol. Med.43(5),2241-2251(2019)
