Scoparone
Cat. No.:YN482391
CAS No. :120-08-1
产品名称: | Scoparone |
CAS No.: | 120-08-1 |
Chemical Name: | 6,7-dimethoxy-2H-1-benzopyran-2-one |
Synonyms: | Aesculetin dimethyl ether,Scoparon,6,7-dimethoxycoumarin,滨蒿内酯,6,7-Dimethylesculetin,Escoparone |
分子量: | 206.19 |
分子式: | C₁₁H₁₀O₄ |
SMILES: | O=C1C=CC2=CC(OC)=C(OC)C=C2O1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Scoparone 从毛蒿中分离出来的,具有抗凝血,抗血管舒张作用,抗炎活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Fu, B., Su, Y., Ma, X., et al.Scoparone attenuates angiotensin II-induced extracellular matrix remodeling in cardiac fibroblastsJ. Pharmacol. Sci.137(2),110-115(2018)
Jung, S.H., Lee, G.B., Ryu, Y., et al.Inhibitory effects of scoparone from chestnut inner shell on platelet-derived growth factor-BB-induced vascular smooth muscle cell migration and vascular neointima hyperplasiaJ. Sci. Food Agric.99(9),4397-4406(2019)
Liu, B., Deng, X., Jiang, Q., et al.Scoparone alleviates inflammation, apoptosis and fibrosis of non-alcoholic steatohepatitis by suppressing the TLR4/NF-κB signaling pathway in miceInt. Immunopharmacol.75,105797(2019)
Son, D.J., Lee, G.R., Oh, S., et al.Gastroprotective efficacy and safety evaluation of scoparone derivatives on experimentally induced gastric lesions in rodentsNutrients7(3),1945-1964(2015)
Choi, Y.H., and Yan, G.H.Anti-allergic effects of scoparone on mast cell-mediated allergy modelPhytomedicine16(12),1089-1094(2009)