Hederagenin
Cat. No.：YN482401
| 产品名称: | Hederagenin |
| CAS No.: | 465-99-6 |
| Chemical Name: | (4α)-3β,23-dihydroxy-olean-12-en-28-oic acid |
| Synonyms: | 常春藤皂苷元 |
| 分子量: | 472.70 |
| 分子式: | C₃₀H₄₈O₄ |
| SMILES: | CC1(C)CC[C@@](CC[C@]2(C)C3=CC[C@@]4([H])[C@@]2(C)CC[C@]5([H])[C@]4(C)CC[C@H](O)[C@]5(CO)C)(C(O)=O)[C@@]3([H])C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hederagenin是三萜皂苷，能够抑制细胞中由于LPS刺激引起的 iNOS, COX-2,和 NF-κB的表达。 |
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Jayasinghe, L., Shimada, H., Hara, N., et al.Hederagenin glycosides from Pometia eximiaPhytochemistry40(3),891-897(1995)
Kim, E.H., Baek, S., Shin, D., et al.Hederagenin induces apoptosis in cisplatin-resistant head and neck cancer cells by inhibiting the Nrf2-ARE antioxidant pathwayOxid. Med. Cell. Longev.,5498908(2017)
Lu, S.-H., Guan, J.-H., Huang, Y.-L., et al.Experimental study of antiatherosclerosis effects with hederagenin in ratsEvid. Based Complement. Alternat. Med.,456354(2015)
Kim, G.-J., Song, D.H., Yoo, H.S., et al.Hederagenin supplementation alleviates the pro-inflammatory and apoptotic response to alcohol in ratsNutrients9(1),E41(2017)
Wu, A.-G., Zeng, W., Wong, V.K.-W., et al.Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-micePharmacol. Res.115,25-44(2017)
