Mollugin
Cat. No.：YN482418
| 产品名称: | Mollugin |
| CAS No.: | 55481-88-4 |
| Chemical Name: | 6-hydroxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5-carboxylic acid, methyl ester |
| Synonyms: | 大叶茜草素 |
| 分子量: | 284.31 |
| 分子式: | C₁₇H₁₆O₄ |
| SMILES: | O=C(C1=C(C=CC(C)(C)O2)C2=C3C=CC=CC3=C1O)OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mollugin 是Rubia cordifolia L.中主要的一种生物活性成分。Mollugin 通过抑制 TNF-α 诱导的 NF-κB 激活起抗癌疗效。Mollugin 能通过 p38-Smad 信号通路增强 BMP-2 的成骨作用。 |
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Idhayadhulla, A., Xia, L., Lee, Y.R., et al.Synthesis of novel and diverse mollugin analogues and their antibacterial and antioxidant activitiesBioorg. Chem.52,77-82(2014)
Matsuda, D., Ohshiro, T., Ohba, M., et al.The molecular target of rubimaillin in the inhibition of lipid droplet accumulation in macrophagesBiol. Pharm. Bull.32(8),1317-1320(2009)
Moon, S.-H., Kim, I., and Kim, S.H.Mollugin enhances the osteogenic action of BMP-2 via the p38-Smad signaling pathwayArch. Pharm. Res.40(11),1328-1335(2017)
Wang, Z., Li, M.Y., Mi, C., et al.Mollugin has an anti-cancer therapeutic effect by inhibiting TNF-α-induced NF-κB activationInt. J. Mol. Sci.18(8),1619(2017)
