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1,4-Dicaffeoylquinic acid

Cat. No.:YN482431

  • CAS No. :1182-34-9

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    • 参考文献
    • 产品名称: 1,4-Dicaffeoylquinic acid
      CAS No.: 1182-34-9
      Chemical Name: (1α,3R,4α,5R)-rel-1,4-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,5-dihydroxy-cyclohexanecarboxylic acid
      Synonyms:1,4-二咖啡酰奎宁酸; 1,4-DCQA
      分子量:516.45
      分子式:C₂₅H₂₄O₁₂
      SMILES:OC1=CC=C(/C=C/C(O[C@H]2[C@H](O)C[C@@](C(O)=O)(OC(/C=C/C3=CC(O)=C(O)C=C3)=O)C[C@H]2O)=O)C=C1O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 1,4-Dicaffeoylquinic acid (1,4-DCQA) 是从苍耳子中得到的苯丙素类物质,能够抑制 LPS 诱导的 TNF-α 的产生,具有抗炎作用。
      IC50和靶点:
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    • Alberati, D., Moreau, J.-L., Lengyel, J., et al.Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophreniaNeuropharmacology62(2),1152-1161(2012)

      Cao, W., Fang, Y., Wu, T., et al.Insights from multispectral and molecular docking investigation on the xanthine oxidase inhibition by 1,4-dicaffeoylquinic acidJ. Mol. Struct.1219,128475(2020)

      Ha, J.H., and Park, S.N.Mechanism underlying inhibitory effect of six dicaffeoylquinic acid isomers on melanogenesis and the computational molecular modeling studiesBioorg. Med. Chem.26(14),4201-4208(2018)

      Preziosi, P., Loscalzo, B., and Marmo, E.Comparison of choleretic effects of CYN and Na-dehydrocholateExperientia15(4),135-138(1959)

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