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10-Gingerol

Cat. No.:YN482458

  • CAS No. :23513-15-7

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 10-Gingerol
      CAS No.: 23513-15-7
      Chemical Name: 5S-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-tetradecanone
      Synonyms:10-姜酚
      分子量:350.49
      分子式:C₂₁H₃₄O₄
      SMILES:CCCCCCCCC[C@H](O)CC(CCC1=CC=C(O)C(OC)=C1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 10-Gingerol 是姜根脂的一种主要刺激性成分,具有抗炎、抗氧化和抗增殖活性。10-Gingerol 能抑制 MDA-MB-231 肿瘤细胞的增殖,其 IC50值为 12.1 μM。
      IC50和靶点:
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    • Dugasani, S., Pichika, M.R., Nadarajah, V.D., et al.Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaolJ. Ethnopharmacol.127(2),515-520(2010)

      Ali, R.A., Gandhi, A.A., Dai, L., et al.Antineutrophil properties of natural gingerols in models of lupusJCI Insight6(3),e138385(2021)

      Hiserodt, R.D., Franzblau, S.G., and Rosen, R.T.Isolation of 6-, 8-, and 10-gingerol from ginger rhizome by HPLC and preliminary evaluation of inhibition of Mycobacterium avium and Mycobacterium tuberculosisJ. Agric. Food Chem.46(7),2504-2508(1998)

      Bernard, M.M., McConnery, J.R., and Hoskin, D.W.[10]-Gingerol, a major phenolic constituent of ginger root, induces cell cycle arrest and apoptosis in triple-negative breast cancer cellsExp. Mol. Pathol.102(2),370-376(2017)

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