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Loganic acid

Cat. No.:YN482474

  • CAS No. :22255-40-9

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    • 参考文献
    • 产品名称: Loganic acid
      CAS No.: 22255-40-9
      Chemical Name: (1S,4aS,6S,7R,7aS)-1-(β-D-glucopyranosyloxy)-1,4a,5,6,7,7a-hexahydro-6-hydroxy-7-methyl-cyclopenta[c]pyran-4-carboxylic acid
      Synonyms:马钱苷酸
      分子量:376.36
      分子式:C₁₆H₂₄O₁₀
      SMILES:O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H]2[C@@]([C@H]3C)([H])[C@@](C[C@@H]3O)([H])C(C(O)=O)=CO2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Loganic acid 是从山茱萸果实中分离得到的一种环烯醚萜。Loganic acid 能调节饮食引起的动脉粥样硬化和氧化还原状态。Loganic acid 具有很强的自由基清除活性,对重金属介导的毒性有显著的细胞保护作用。
      IC50和靶点:
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    • Coscia, C.J., Guarnaccia, R., and Botta, L.Monoterpene biosynthesis. I. Occurrence and mevalonoid origin of gentiopicroside and loganic acid in Swertia caroliniensisBiochemistry8(12),5036-5543(1969)

      Suh, H.-W., Lee, K.-B., Kim, K.-S., et al.A bitter herbal medicine Gentiana scabra root extract stimulates glucagon-like peptide-1 secretion and regulates blood glucose in db/db mouseJ. Ethnopharmacol.172,219-226(2015)

      Park, E., Kim, J., Yeo, S., et al.Antiadipogenic effects of loganic acid in 3T3-L1 preadipocytes and ovariectomized miceMolecules23(7),E1663(2018)

      Sozański, T., Kucharska, A.Z., Rapak, A., et al.Iridoid-loganic acid versus anthocyanins from the Cornus mas fruits (cornelian cherry): Common and different effects on diet-induced atherosclerosis, PPARs expression and inflammationAtherosclerosis254,151-160(2016)

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