Nomilin
Cat. No.：YN482483
CAS No. ：1063-77-0
| 产品名称: | Nomilin |
| CAS No.: | 1063-77-0 |
| Chemical Name: | (1S,3aS,4aR,4bR,6aR,11S,11aR,11bR,13aS)-11-(acetyloxy)-1-(3-furanyl)decahydro-4b,7,7,11a,13a-pentamethyl-oxireno[4,4a]-2-benzopyrano[6,5-g][2]benzoxepin-3,5,9(3aH,4bH,6H)-trione |
| Synonyms: | 诺米林 |
| 分子量: | 514.56 |
| 分子式: | C₂₈H₃₄O₉ |
| SMILES: | C[C@]([C@@](CC1)([H])[C@]2([C@H](CC3=O)OC(C)=O)C)(C(C[C@@]2([H])C(C)(O3)C)=O)[C@@]4([C@@H]5O4)[C@@]1([C@H](C6=COC=C6)OC5=O)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nomilin 是从柑桔类提取物中获得的柠檬苦素类化合物。Nomilin 是一种抗肥胖症和降糖药。 |
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Lam, L., Li, Y., and Hasegawa, S.Effects of citrus limonoids on glutathione S-transferase activity in miceJ. Agric. Food Chem.37(4),878-880(1989)
Battinelli, L., Mengoni, F., Lichtner, M., et al.Effect of limonin and nomilin on HIV-1 replication on infected human mononuclear cellsPlanta Med.69(10),910-913(2003)
Pratheeshkumar, P., and Kuttan, G.Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9Eur. J. Pharmacol.668(3),450-458(2011)
Ono, E., Inoue, J., Hashidume, T., et al.Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat dietBiochem. Biophys. Res. Commun.410(3),677-681(2011)
Raphael, T.J., and Kuttan, G.Effect of naturally occurring triterpenoids glycyrrhizic acid, ursolic acid, oleanolic acid and nomilin on the immune systemPhytomedicine10(6-7),483-489(2003)
