Kirenol
Cat. No.：YN482487
| 产品名称: | Kirenol |
| CAS No.: | 52659-56-0 |
| Chemical Name: | (α7R,1R,3S,4aS,4bR,7S,10aS)-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-3-hydroxy-α7-(hydroxymethyl)-1,4a,7-trimethyl-1,7-phenanthrenedimethanol |
| Synonyms: | 奇任醇 |
| 分子量: | 338.48 |
| 分子式: | C₂₀H₃₄O₄ |
| SMILES: | C[C@]([C@@](CC1)([H])[C@]2(C)CO)(C[C@H](O)C2)[C@@]3([H])C1=C[C@]([C@@H](O)CO)(C)CC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Kirenol 是从Siegesbeckia orientalis分离得到的，具有抗炎镇痛作用。 |
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Wang, Z.-M., Zhu, S.-G., Wu, Z.-W., et al.Kirenol upregulates nuclear annexin-1 which interacts with NF-κB to attenuate synovial inflammation of collagen-induced arthritis in ratsJ. Ethnopharmacol.137(1),774-782(2011)
Wang, J.P., Zhou, Y.-m., Ye, Y.-j., et al.Topical anti-inflammatory and analgesic activity of kirenol isolated from Siegesbeckia orientaliJ. Ethnopharmacol.137(3),1089-1094(2011)
Wang, J.-P., Zhou, Y.-M., and Zhang, Y.-H.Kirenol production in hairy root culture of Siegesbeckea orientalis and its antimicrobial activityPharmacogn. Mag.8(30),149-155(2012)
Lu, Y., Qian, R., Xiao, J., et al.Kirenol, a compound from Herba Siegesbeckiae, induces apoptosis in human chronic myeloid leukemia K562 cellsPharmazie69(2),148-153(2014)
Xiao, J., Yang, R., Yang, L., et al.Kirenol attenuates experimental autoimmune encephalomyelitis by inhibiting differentiation of Th1 and Th17 cells and inducing apoptosis of effector T cellsSci. Rep.5:9022,(2015)
