Apiin
Cat. No.：YN482494
| 产品名称: | Apiin |
| CAS No.: | 26544-34-3 |
| Chemical Name: | 7-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | Apioside,芹菜苷 |
| 分子量: | 564.49 |
| 分子式: | C₂₆H₂₈O₁₄ |
| SMILES: | O=C(C=C(C1=CC=C(O)C=C1)OC2=CC(O[C@H](O[C@H](CO)[C@@H](O)[C@@H]3O)[C@@H]3O[C@@](OC[C@]4(O)CO)([H])[C@@H]4O)=C5)C2=C5O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Apiin 是Apium graveolens叶片的主要成分之一，具有抗炎特性。Apiin 在体外能抑制亚硝酸盐 (NO) 的产生 (IC50= 0.08 mg/mL)，在 LPS 激活的 J774.A1 细胞中能抑制 iNOS 的表达 (IC50= 0.049 mg/ mL) 。 |
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Cheung, V.W.N., Xue, B., Hernandez-Valladares, M., et al.Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalisPLoS One9(7),e103598(2014)
Jung, Y., Shin, S.Y., Yong, Y., et al.Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationshipsChem. Biol. Drug Des.85(5),574-585(2015)
Mencherini, T., Cau, A., Bianco, G., et al.An extract of Apium graveolens var. dulce leaves: Structure of the major constituent, apiin, and its anti-inflammatory propertiesJ. Pharm. Pharmacol.59(6),891-897(2007)
Li, P., Jia, J., Zhang, D., et al.In vitro and in vivo antioxidant activities of a flavonoid isolated from celery (Apium graveolens L. var. dulce)Food Funct.5(1),50-56(2014)
