Panaxadiol
Cat. No.:YN482499
产品名称: | Panaxadiol |
CAS No.: | 19666-76-3 |
Chemical Name: | 20R,25-epoxy-dammarane-3β,12β-diol |
Synonyms: | 人参二醇; 20(R) |
分子量: | 460.73 |
分子式: | C₃₀H₅₂O₃ |
SMILES: | C[C@@]1(CC[C@@H]2O)[C@](C[C@H]3O)([H])[C@](CC[C@@]1([H])C2(C)C)(C)[C@@]4(C)[C@@]3([H])[C@]([C@](CCC5)(C)OC5(C)C)([H])CC4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 人参二醇 (Panaxadiol) 是从中药人参中分离到的一种新颖的抗肿瘤药物。 |
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Xiao, S., Lin, Z., Wang, X., et al.Synthesis and cytotoxicity evaluation of panaxadiol derivativesChem. Biodivers.17(1),e1900516(2020)
Wang, Z., Li, M.Y., Zhang, Z.H., et al.Panaxadiol inhibits programmed cell death-ligand 1 expression and tumour proliferation via hypoxia-inducible factor (HIF)-1α and STAT3 in human colon cancer cellsPharmacol. Res.155,104727(2020)
Chen, H., Wang, L.-J., Ma, Y.-B., et al.Panaxadiol and panaxatriol derivatives as anti-hepatitis B virus inhibitorsNat. Prod. Bioprospect.4(3),163-174(2014)
Liang, X., Yao, Y., Lin, Y., et al.Panaxadiol inhibits synaptic dysfunction in Alzheimer's disease and targets the Fyn protein in APP/PS1 mice and APP-SH-SY5Y cellsLife Sci.221,35-46(2019)