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Panaxadiol

Cat. No.:YN482499

  • CAS No. :19666-76-3

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    • 参考文献
    • 产品名称: Panaxadiol
      CAS No.: 19666-76-3
      Chemical Name: 20R,25-epoxy-dammarane-3β,12β-diol
      Synonyms:人参二醇; 20(R)
      分子量:460.73
      分子式:C₃₀H₅₂O₃
      SMILES:C[C@@]1(CC[C@@H]2O)[C@](C[C@H]3O)([H])[C@](CC[C@@]1([H])C2(C)C)(C)[C@@]4(C)[C@@]3([H])[C@]([C@](CCC5)(C)OC5(C)C)([H])CC4
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 人参二醇 (Panaxadiol) 是从中药人参中分离到的一种新颖的抗肿瘤药物。
      IC50和靶点:
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    • Xiao, S., Lin, Z., Wang, X., et al.Synthesis and cytotoxicity evaluation of panaxadiol derivativesChem. Biodivers.17(1),e1900516(2020)

      Wang, Z., Li, M.Y., Zhang, Z.H., et al.Panaxadiol inhibits programmed cell death-ligand 1 expression and tumour proliferation via hypoxia-inducible factor (HIF)-1α and STAT3 in human colon cancer cellsPharmacol. Res.155,104727(2020)

      Chen, H., Wang, L.-J., Ma, Y.-B., et al.Panaxadiol and panaxatriol derivatives as anti-hepatitis B virus inhibitorsNat. Prod. Bioprospect.4(3),163-174(2014)

      Liang, X., Yao, Y., Lin, Y., et al.Panaxadiol inhibits synaptic dysfunction in Alzheimer's disease and targets the Fyn protein in APP/PS1 mice and APP-SH-SY5Y cellsLife Sci.221,35-46(2019)

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