Silychristin
Cat. No.：YN482510
| 产品名称: | Silychristin |
| CAS No.: | 33889-69-9 |
| Chemical Name: | (2R,3R)-2-[(2R,3S)-2,3-dihydro-7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-benzofuranyl]-2,3-4H-1-benzopyran-4-one |
| Synonyms: | 水飞蓟汀 |
| 分子量: | 482.44 |
| 分子式: | C₂₅H₂₂O₁₀ |
| SMILES: | O=C1[C@H](O)[C@@H](C2=CC(O)=C(O[C@@H](C3=CC=C(O)C(OC)=C3)[C@@H]4CO)C4=C2)OC5=CC(O)=CC(O)=C15 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Silychristin 是水飞蓟果实中富含的黄酮类化合物，具有抗氧化作用。Silychristin 是甲状腺激素转运体MCT8的有效抑制剂，能强烈抑制 T3 的摄取，IC50为 110 nM。 |
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Johannes, J., Jayarama-Naidu, R., Meyer, F., et al.Silychristin, a flavonolignan derived from the milk thistle, is a potent inhibitor of the thyroid hormone transporter MCT8Endocrinology157(4),1694-1701(2016)
Biedermann, D., Buchta, M., Holečková, V., et al.Silychristin: Skeletal alterations and biological activitiesJ. Nat. Prod.79(12),3086-3092(2016)
Viktorová, J., Dobiasová, S., Řehořová, K., et al.Antioxidant, anti-inflammatory, and multidrug resistance modulation activity of silychristin derivativesAntioxidants 8(8),303(2019)
