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Monotropein

Cat. No.:YN482511

  • CAS No. :5945-50-6

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Monotropein
      CAS No.: 5945-50-6
      Chemical Name: (1S,4aS,7R,7aS)-1-(β-D-glucopyranosyloxy)-1,4a,7,7a-tetrahydro-7-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic acid
      Synonyms:Monotropeine,水晶兰苷
      分子量:390.34
      分子式:C₁₆H₂₂O₁₁
      SMILES:O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H]2[C@@]([C@@]3(O)CO)([H])[C@@](C=C3)([H])C(C(O)=O)=CO2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Monotropein 源于Morinda officinalis。 Monotropein 抑制硫酸葡聚糖硫酸钠诱导的结肠炎小鼠模型中炎性因子的表达。
      IC50和靶点:
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    • Wang, C., Mao, C., Lou, Y., et al.Monotropein promotes angiogenesis and inhibits oxidative stress-induced autophagy in endothelial progenitor cells to accelerate wound healingJ. Cell. Mol. Med.22(3),1583-1600(2018)

      Wang, F., Wu, L., Li, L., et al.Monotropein exerts protective effects against IL-1β-induced apoptosis and catabolic responses on osteoarthritis chondrocytesInt. Immunopharmacol.23(2),575-580(2014)

      Shin, J.-S., Yun, K.-J., Chung, K.-S., et al.Monotropein isolated from the roots of Morinda officinalis ameliorates proinflammatory mediators in RAW 264.7 macrophages and dextran sulfate sodium (DSS)-induced colitis via NF-κB inactivationFood Chem. Toxicol.53,263-271(2013)

      Zhang, Z., Zhang, Q., Yang, H., et al.Monotropein isolated from the roots of Morinda officinalis increases osteoblastic bone formation and prevents bone loss in ovariectomized miceFitoterapia110,166-172(2016)

      Choi, J., Lee, K.-T., Choi, M.-Y., et al.Antinociceptive anti-inflammatory effect of Monotropein isolated from the root of Morinda officinalisBiol. Pharm. Bull.28(10),1915-1918(2005)

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