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Neoandrographolide

Cat. No.:YN482534

  • CAS No. :27215-14-1

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    • 生物活性
    • 参考文献
    • 产品名称: Neoandrographolide
      CAS No.: 27215-14-1
      Chemical Name: 3-[2-[(1R,4aS,5R,8aS)-5-[(β-D-glucopyranosyloxy)methyl]decahydro-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethyl]-2(5H)-furanone
      Synonyms:新穿心莲内酯; Neoandrographiside
      分子量:480.59
      分子式:C₂₆H₄₀O₈
      SMILES:C[C@@]([C@@H]1CCC2=CCOC2=O)(CCC3)[C@@](CCC1=C)([H])[C@]3(C)CO[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 新穿心莲内酯 (Neoandrographolide)是从穿心莲中分离到的二萜类化合物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Jarukamjorn, K., and Nemoto, N.Pharmacological aspects of Andrographis paniculata on health and its major diterpenoid constituent andrographolideJ. Health Sci.54(4),370-381(2008)

      Batkhuu, J., Hattori, K., Takano, F., et al.Suppression of NO production in activated macrophages in vitro and ex vivo by neoandrographolide isolated from Andrographis paniculataBiol. Pharm. Bull.25(9),1169-1174(2002)

      Gong, C., Xu, C., Ji, L., et al.A novel semi-synthetic andrographolide analogue A5 inhibits tumor angiogenesis via blocking the VEGFR2-p38/ERK1/2 signal pathwayBiosci. Trends7(5),230-236(2013)

      Basak, A., Cooper, S., Roberge, A.G., et al.Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl estersBiochem. J.338(Pt 1),107-113(1999)

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