Phellodendrine chloride
Cat. No.：YN482537
CAS No. ：104112-82-5
| 产品名称: | Phellodendrine chloride |
| CAS No.: | 104112-82-5 |
| Chemical Name: | 5,8,13,13aS-tetrahydro-2,11-dihydroxy-3,10-dimethoxy-7S-methyl-6H-dibenzo[a,g]quinolizinium, monochloride |
| Synonyms: | 盐酸黄柏碱 |
| 分子量: | 377.86 |
| 分子式: | C₂₀H₂₄ClNO₄ |
| SMILES: | C[N@@+]12CCC3=CC(OC)=C(O)C=C3[C@]1([H])CC4=CC(O)=C(OC)C=C4C2.[Cl-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Phellodendrine chloride 是Phellodendron amurense中的一种生物碱。Phellodendrine chloride 能通过巨胞饮抑制营养物质的吸收来抑制 KRAS 突变的胰腺癌细胞的增殖。 |
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Thu, P.M., Zheng, Z.-G., Zhou, Y.-P., et al.Phellodendrine chloride suppresses proliferation of KRAS mutated pancreatic cancer cells through inhibition of nutrients uptake via macropinocytosisEur. J. Pharmacol.850,23-34(2019)
Kim, Y.J., Lim, H.-Y., Kim, Y., et al.Phytochemical quantification and the in vitro acetylcholinesterase inhibitory activity of Phellodendron chinense and its componentsMolecules22(6),925(2017)
Mori, H., Fuchigami, M., Inoue, N., et al.Principle of the bark of Phellodendron amurense to suppress the cellular immune response: effect of phellodendrine on cellular and humoral immune responsesPlanta Med.61(1),45-49(1995)
