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Senkyunolide H

Cat. No.:YN482540

  • CAS No. :94596-27-7

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    • 产品名称: Senkyunolide H
      CAS No.: 94596-27-7
      Chemical Name: (3Z,6R,7S)-rel-3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone
      Synonyms:洋川芎内酯 H
      分子量:224.25
      分子式:C₁₂H₁₆O₄
      SMILES:O=C1O/C(C2=C1[C@H](O)[C@H](O)CC2)=C\CCC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Senkyunolide H 是从Ligusticum chuanxiongHort 中提取得到的天然化合物。
      IC50和靶点:
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      In Vivo:
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    • Yan, R., Li, S.-L., Chung, H.-S., et al.Simultaneous quantification of 12 bioactive components of Ligusticum chuanxiong Hort. by high-performance liquid chromatographyJ. Pharm. Biomed. Anal.37(1),87-95(2005)

      Qi, H., Siu, S.O., Chen, Y., et al.Senkyunolides reduce hydrogen peroxide-induced oxidative damage in human liver HepG2 cells via induction of heme oxygenase-1Chem. Biol. Interact.183(3),380-389(2010)

      Kobayashi, S., Mimura, Y., Notoya, K., et al.Antiproliferative effects of the traditional Chinese medicine shimotsu-to, its component cnidium rhizome and derived compounds on primary cultures of mouse aorta smooth muscle cellsJpn. J. Pharmacol.60(4),397-401(1992)

      Yang, D., Liu, T., Jiang, G., et al.Senkyunolide H attenuates osteoclastogenesis and postmenopausal osteoporosis by regulating the NF-κB, JNK and ERK signaling pathwaysBiochem. Biophys. Res. Commun.533(3),510-518(2020)

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