Oxysophocarpine
Cat. No.：YN482541
CAS No. ：26904-64-3
| 产品名称: | Oxysophocarpine |
| CAS No.: | 26904-64-3 |
| Chemical Name: | (4R,7aS,13aR,13bR,13cS)-2,3,6,7,7a,8,13,13a,13b,13c-decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 4-oxide |
| Synonyms: | 氧卡地平 |
| 分子量: | 262.35 |
| 分子式: | C₁₅H₂₂N₂O₂ |
| SMILES: | O=C1C=CC[C@]2([H])[C@@]3([H])CCC[N@@+]4([O-])[C@@]3([H])[C@](CCC4)([H])CN21 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Oxysophocarpine 是一种提取自海藻的生物碱。Oxysophocarpine 对中枢神经系统和周围神经系统具有神经保护作用和抗伤害感受作用。Oxysophocarpine 抑制口腔鳞状细胞癌 (OSCC) 的生长和转移。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Zhu, Q.-L., Li, Y.-X., Zhou, R., et al.Neuroprotective effects of oxysophocarpine on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusionPharm. Biol.52(8),1052-1059(2014)
Liu, R., Peng, J., Wang, H., et al.Oxysophocarpine retards the growth and metastasis of oral squamous cell carcinoma by targeting the Nrf2/HO-1 axisCell Physiol. Biochem.49(5),1717-1733(2018)
Yang, Y., Li, Y.-X., Wang, H.-L., et al.Oxysophocarpine ameliorates carrageenan-induced inflammatory pain via inhibiting expressions of prostaglandin E2 and cytokines in micePlanta Med.81(10),791-797(2015)
