Monocrotaline
Cat. No.：YN482543
CAS No. ：315-22-0
| 产品名称: | Monocrotaline |
| CAS No.: | 315-22-0 |
| Chemical Name: | (3R,4R,5R)-4,5,8,10,12,13,13aR,13bR-octahydro-4,5-dihydroxy-3,4,5-trimethyl-2H-[1,6]dioxacycloundecino[2,3,4-gh]pyrrolizine-2,6(3H)-dione |
| Synonyms: | 野百合碱; Crotaline |
| 分子量: | 325.36 |
| 分子式: | C₁₆H₂₃NO₆ |
| SMILES: | O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C)[C@@](C)(O)[C@@](C)(O)C3=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Monocrotaline是从猪屎豆植物的种子提取的吡咯里西啶生物碱，用于在啮齿动物中诱导肺动脉高血压。 |
| IC50和靶点: | [{name:"OCT1:36.8 μM (IC50)"},{name: "OCT2:1852.6 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Gomez-Arroyo, J.G., Farkas, L., Alhussaini, A.A., et al.The monocrotaline model of pulmonary hypertension in perspectiveAm. J. Physiol. Lung Cell. Mol. Physiol.302(4),L363-L369(2012)
Maarman, G., Lecour, S., Butrous, G., et al.A comprehensive review: The evolution of animal models in pulmonary hypertension research; are we there yet?Pulm.Circ.3(4),739-756(2013)
