Isorhynchophylline
Cat. No.：YN482549
CAS No. ：6859-01-4
| 产品名称: | Isorhynchophylline |
| CAS No.: | 6859-01-4 |
| Chemical Name: | (αE,1′S,6′R,7′S,8′aS)-6′-ethyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, methyl ester |
| Synonyms: | 异钩藤碱 |
| 分子量: | 384.47 |
| 分子式: | C₂₂H₂₈N₂O₄ |
| SMILES: | O=C(NC1=C2C=CC=C1)[C@@]32[C@@](C[C@H](/C(C(OC)=O)=C\OC)[C@@H](CC)C4)([H])N4CC3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 异钩藤碱 (Isorhynchophylline) 是从钩藤中分离得到的生物碱类化合物，能够降血压、舒张血管、保护神经免于局部缺血造成损伤。 |
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Xian, Y.-F., Lin, Z.-X., Mao, Q.-Q., et al.Protective effect of isorhynchophylline against β-amyloid-induced neurotoxicity in PC12 cellsCell Mol. Neurobiol.32(3),353-360(2012)
Kang, T.-H., Murakami, Y., Takayama, H., et al.Protective effect of rhynchophylline and isorhynchophylline on in vitro ischemia-induced neuronal damage in the hippocampus: Putative neurotransmitter receptors involved in their actionLife Sci.76(3),331-343(2004)
Lee, H., Baek, S.H., Lee, J.H., et al.Isorhynchophylline, a potent plant plkaloid, induces apoptotic and anti-metastatic effects in human hepatocellular carcinoma cells through the modulation of diverse cell signaling cascadesInt. J. Mol. Sci.18(5),E1095(2017)
Guo, H., Zhang, H., Cui, Y., et al.Isorhynchophylline protects against pulmonary arterial hypertension and suppresses PASMCs proliferationBiochem. Biophys. Res. Commun.450(1),729-734(2014)
