Ginkgolide J
Cat. No.：YN482552
| 产品名称: | Ginkgolide J |
| CAS No.: | 107438-79-9 |
| Chemical Name: | (1S,2R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-3-(1,1-dimethylethyl)hexahydro-2,4,7b-trihydroxy-8-methyl-9H-1,7a-(epoxymethano)-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3′,2′:3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione |
| Synonyms: | BN 52024,7-beta-Hydroxyginkgolide A,银杏内酯 J,银杏内酯J |
| 分子量: | 424.40 |
| 分子式: | C₂₀H₂₄O₁₀ |
| SMILES: | O[C@@]1([C@@H]2C)C3(O[C@@](OC4=O)([H])C5([C@H]4O)[C@H](C(C)(C)C)[C@@H](O)[C@@]6([H])OC3=O)[C@@]56C[C@]1([H])OC2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ginkgolide J 是银杏叶中非黄酮部分的主要成分，IC50的范围为 12-54 µM，具有神经保护和抗神经元凋亡的能力。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Braquet, P., Esanu, A., Buisine, E., et al.Recent progress in ginkgolide researchMed. Res. Rev.11(3),295-355(1991)
Koch, E.Inhibition of platelet activating factor (PAF)-induced aggregation of human thrombocytes by ginkgolides: Considerations on possible bleeding complications after oral intake of Ginkgo biloba extractsPhytomedicine12(1-2),10-16(2005)
Vitolo, O., Gong, B., Cao, Z., et al.Protection against β-amyloid induced abnormal synaptic function and cell death by Ginkgolide JNeurobiol. Aging30(2),257-265(2009)
