Alisol B
Cat. No.:YN482559
CAS No. :18649-93-9
产品名称: | Alisol B |
CAS No.: | 18649-93-9 |
Chemical Name: | (8α,9β,11β,14β,23S,24R)-24,25-epoxy-11,23-dihydroxy-dammar-13(17)-en-3-one |
Synonyms: | 泽泻醇 B |
分子量: | 472.70 |
分子式: | C₃₀H₄₈O₄ |
SMILES: | C[C@]([C@@]1(C2=C([C@H](C)C[C@@H]([C@]3([H])C(C)(C)O3)O)CC1)C)(CC[C@@]4([H])C5(C)C)[C@]([C@H](C2)O)([H])[C@]4(CCC5=O)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Alisol B 是一种潜在的研究骨科疾病的化合物,通过对破骨细胞的分化以其功能发挥作用。 |
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Law, B.Y.K., Wang, M., Ma, D.-L., et al.Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosisMol. Cancer Ther.9(3),718-730(2010)
Lee, J.-W., Kobayashi, Y., Nakamichi, Y., et al.Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in miceBiochem. Pharmacol.80(3),352-361(2010)
Lee, J.H., Kwon, O.S., Jin, H.-G., et al.The rhizomes of Alisma orientale and alisol derivatives inhibit allergic response and experimental atopic dermatitisBiol. Pharm. Bull.35(9),1581-1587(2012)