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Alisol B

Cat. No.:YN482559

  • CAS No. :18649-93-9

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    • 产品名称: Alisol B
      CAS No.: 18649-93-9
      Chemical Name: (8α,9β,11β,14β,23S,24R)-24,25-epoxy-11,23-dihydroxy-dammar-13(17)-en-3-one
      Synonyms:泽泻醇 B
      分子量:472.70
      分子式:C₃₀H₄₈O₄
      SMILES:C[C@]([C@@]1(C2=C([C@H](C)C[C@@H]([C@]3([H])C(C)(C)O3)O)CC1)C)(CC[C@@]4([H])C5(C)C)[C@]([C@H](C2)O)([H])[C@]4(CCC5=O)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Alisol B 是一种潜在的研究骨科疾病的化合物,通过对破骨细胞的分化以其功能发挥作用。
      IC50和靶点:
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    • Law, B.Y.K., Wang, M., Ma, D.-L., et al.Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosisMol. Cancer Ther.9(3),718-730(2010)

      Lee, J.-W., Kobayashi, Y., Nakamichi, Y., et al.Alisol-B, a novel phyto-steroid, suppresses the RANKL-induced osteoclast formation and prevents bone loss in miceBiochem. Pharmacol.80(3),352-361(2010)

      Lee, J.H., Kwon, O.S., Jin, H.-G., et al.The rhizomes of Alisma orientale and alisol derivatives inhibit allergic response and experimental atopic dermatitisBiol. Pharm. Bull.35(9),1581-1587(2012)

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