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Lithospermic acid

Cat. No.:YN482566

  • CAS No. :28831-65-4

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    • 产品名称: Lithospermic acid
      CAS No.: 28831-65-4
      Chemical Name: (2S,3S)-4-[(1E)-3-[(1R)-1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy]-3-oxo-1-propen-1-yl]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofurancarboxylic acid
      Synonyms:紫草酸; (+)
      分子量:538.46
      分子式:C₂₇H₂₂O₁₂
      SMILES:O=C([C@@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=C(O)C=CC(/C=C/C(O[C@@H](C(O)=O)CC4=CC=C(O)C(O)=C4)=O)=C13)O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Lithospermic acid ((+)-Lithospermic acid) 是从丹参中分离出的一种植物来源的多环酚类羧酸,对 CCl4诱导的急性和体外肝损伤具有抗氧化和保肝活性。
      IC50和靶点:
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    • Liu, X., Chen, R., Shang, Y., et al.Lithospermic acid as a novel xanthine oxidase inhibitor has anti-inflammatory and hypouricemic effects in ratsChem. Biol. Interact.176(2-3),137-142(2008)

      Chan, K.W.K., and Ho, W.S.Anti-oxidative and hepatoprotective effects of lithospermic acid against carbon tetrachloride-induced liver oxidative damage in vitro and in vivoOncol. Rep.34(2),673-680(2015)

      Abd-Elazem, I.S., Chen, H.S., Bates, R.B., et al.Isolation of two highly potent and non-toxic inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase from Salvia miltiorrhizaAntiviral Res.55(1),91-106(2002)

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