Notoginsenoside Ft1
Cat. No.:YN482609
产品名称: | Notoginsenoside Ft1 |
CAS No.: | 155683-00-4 |
Chemical Name: | (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside |
Synonyms: | 三七皂苷FT1,三七皂甙 Ft1 |
分子量: | 917.13 |
分子式: | C₄₇H₈₀O₁₇ |
SMILES: | C[C@@]([C@@]12C)(CC[C@@]3([H])C4(C)C)[C@@](C[C@@H](O)[C@]1([H])[C@]([C@](C)(O)CC/C=C(C)/C)([H])CC2)([H])[C@]3(CC[C@@H]4O[C@@](O[C@H](CO)[C@@H](O)[C@@H]5O)([H])[C@@H]5O[C@@](O[C@H](CO)[C@@H](O)[C@@H]6O)([H])[C@@H]6O[C@@](OC[C@@H](O)[C@@H]7O)([H])[C@@H]7O)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 三七皂苷Ft1(Notoginsenoside Ft1)是植物分离三七皂苷,刺激血管生成。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Shen, K., Ji, L., Gong, C., et al.Notoginsenoside Ft1 promotes angiogenesis via HIF-1α mediated VEGF secretion and the regulation of PI3K/AKT and Raf/MEK/ERK signaling pathwaysBiochem. Pharmacol.84(6),784-792(2012)
Gao, B., Shi, H.-L., Li, X., et al.p38 MAPK and ERK1/2 pathways are involved in the pro-apoptotic effect of notoginsenoside Ft1 on human neuroblastoma SH-SY5Y cellsLife Sci.108(2),63-70(2014)
Shen, K., Leung, S.W.S., Ji, L., et al.Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteriesBiochem. Pharmacol.88(1),66-74(2014)
Gao, B., Huang, L., Liu, H., et al.Platelet P2Y12 receptors are involved in the haemostatic effect of notoginsenoside Ft1, a saponin isolated from Panax notoginsengBr. J. Pharmacol.171(1),214-223(2014)
Zhang, E., Gao, B., Yang, L., et al.Notoginsenoside Ft1 promotes fibroblast proliferation via PI3K/Akt/mTOR signaling pathway and benefits wound healing in genetically diabetic miceJ. Pharmacol. Exp. Ther.356(2),324-332(2016)