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beta-Mangostin

Cat. No.:YN482620

  • CAS No. :20931-37-7

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: beta-Mangostin
      CAS No.: 20931-37-7
      Chemical Name: 1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
      Synonyms:β-Mangostin
      分子量:424.49
      分子式:C₂₅H₂₈O₆
      SMILES:C1(=O)C2=C(C=C(O)C(OC)=C2C/C=C(/C)\C)OC2=C1C(O)=C(C/C=C(/C)\C)C(OC)=C2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: beta-Mangostin (β-Mangostin) 是存在Cratoxylum arborescens中的一种氧杂蒽酮化合物,对各种癌症 (如肝细胞癌、白血病) 具有强大的抗癌活性。
      IC50和靶点:
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    • Iinuma, M., Tosa, H., Tanaka, T., et al.Antibacterial activity of xanthones from guttiferaeous plants against methicillin-resistant Staphylococcus aureusJ. Pharm. Pharmacol.48(8),861-865(1996)

      Likhitwitayawuid, K., Phadungcharoen, T., and Krungkrai, J.Antimalarial xanthones from Garcinia cowaPlanta. Med.64(1),70-72(1998)

      Suksamrarn, S., Suwannapoch, N., Phakhodee, W., et al.Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostanaChem. Pharm. Bull. (Tokyo)51(7),857-859(2003)

      Jiang, H.Z., Quan, X.F., Tian, W.X., et al.Fatty acid synthase inhibitors of phenolic constituents isolated from Garcinia mangostanaBioorg. Med. Chem. Lett.20(20),6045-6047(2010)

      Syam, S., Bustamam, A., Abdullah, R., et al.β-Mangostin induces p53-dependent G2/M cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway and NfkB suppression in MCF-7 cellsJ. Funct. Foods6(1),290-304(2014)

      Syam, S., Bustamam, A., Abdullah, R., et al.β Mangostin suppress LPS-induced inflammatory response in RAW 264.7 macrophages in vitro and carrageenan-induced peritonitis in vivoJ. Ethnopharmacol.153(2),435-445(2014)

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