Tigogenin
Cat. No.：YN482659
CAS No. ：77-60-1
| 产品名称: | Tigogenin |
| CAS No.: | 77-60-1 |
| Chemical Name: | (3β,5α,25R)-spirostan-3-ol |
| Synonyms: | 剑麻皂苷元 |
| 分子量: | 416.64 |
| 分子式: | C₂₇H₄₄O₃ |
| SMILES: | [H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@H]3C)C[C@@]4([H])[C@]5([H])CC[C@@]6([H])C[C@@H](O)CC[C@]6(C)[C@@]5([H])CC[C@]4(C)[C@]13[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tigogenin 是一种甾体皂甙元，广泛用于合成甾体类药物。Tigogenin 抑制小鼠骨髓基质细胞脂肪细胞分化，诱导成骨细胞分化。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Cripps, A.L., and Blunden, G.A quantitative gas-liquid chromatographic method for the estimation of hecogenin and tigogenin in the leaves, juice and sapogenin concentrates of Agave sisalanaSteroids31(5),661-669(1978)
Zhou, H., Yang, X., Wang, N., et al.Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cellsMol. Cell Endocrinol.270(1-2),17-22(2007)
Upadhyay, S.K., Creech, C.C., Bowdy, K.L., et al.Synthesis and antifungal activity of functionalized 2,3-spirostane isomersBioorg. Med. Chem. Lett.21(10),2826-2831(2011)
Peana, A.T., Moretti, M.D., Manconi, V., et al.Anti-inflammatory activity of aqueous extracts and steroidal sapogenins of Agave americanaPlanta Med.63(3),199-202(1997)
