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Tiliroside

Cat. No.:YN482666

  • CAS No. :20316-62-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Tiliroside
      CAS No.: 20316-62-5
      Chemical Name: 5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-β-D-glucopyranosyl]oxy]-4H-1-benzopyran-4-one
      Synonyms:银椴甙
      分子量:594.52
      分子式:C₃₀H₂₆O₁₃
      SMILES:O=C1C(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)COC(/C=C/C3=CC=C(O)C=C3)=O)=C(C4=CC=C(O)C=C4)OC5=CC(O)=CC(O)=C51.[E]
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tiliroside 是一种糖苷类黄酮,具有抗糖尿病作用。Tiliroside 是 α-淀粉酶(α-amylase)的非竞争性抑制剂,Ki值为 84.2 μM。Tiliroside 抑制胃肠道中碳水化合物的消化和葡萄糖的吸收。
      IC50和靶点:
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    • Grochowski, D.M., Locatelli, M., Granica, S., et al.A review on the dietary flavonoid tilirosideCompr. Rev. Food Sci. Food Saf.17(5),1395-1421(2018)

      Karioti, A., Ceruso, M., Carta, F., et al.New natural product carbonic anhydrase inhibitors incorporating phenol moietiesBioorg. Med. Chem.23(22),7219-7225(2015)

      Rao, Y.K., Geethangili, M., Fang, S.-H., et al.Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: a comparative studyFood Chem. Toxicol.45(9),1770-1776(2007)

      Sala, A., Recio, M.C., Schinella, G.R., et al.Assessment of the anti-inflammatory activity and free radical scavenger activity of tilirosideEur. J. Pharmacol.461(1),53-61(2003)

      Goto, T., Teraminami, A., Lee, J.-Y., et al.Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic miceJ. Nutr. Biochem.23(7),768-776(2012)

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