Glycodeoxycholic acid monohydrate
Cat. No.：YN482667
| 产品名称: | Glycodeoxycholic acid monohydrate |
| CAS No.: | 1079043-81-4 |
| Chemical Name: | N-[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]-glycine, monohydrate |
| Synonyms: | |
| 分子量: | 467.64 |
| 分子式: | C₂₆H₄₅NO₆ |
| SMILES: | O=C(O)CNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O.O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Glycodeoxycholic acid monohydrate 是一种核受体配体。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Lefebvre, P., Cariou, B., Lien, F., et al.Role of bile acids and bile acid receptors in metabolic regulationPhysiol. Rev.89(1),147-191(2009)
Khurana, S., Raina, H., Pappas, V., et al.Effects of deoxycholylglycine, a conjugated secondary bile acid, on myogenic tone and agonist-induced contraction in rat resistance arteriesPLoS One7(2),e32006(2012)
Shang, Q., Guo, G.L., Honda, A., et al.Bile acid flux through portal but not peripheral veins inhibits CYP7A1 expression without involvement of ileal FGF19 in rabbitsAm. J. Physiol. Gastrointest. Liver Physiol.307(4),G479-G486(2014)
Woolbright, B.L., McGill, M.R., Staggs, V.S., et al.Glycodeoxycholic acid levels as prognostic biomarker in acetaminophen-induced acute liver failure patientsToxicol. Sci.142(2),436-444(2014)
Comhair, S.A.A., McDunn, J., Bennett, C., et al.Metabolomic endotype of asthmaJ. Immunol.195(2),643-650(2015)
