Tabersonine
Cat. No.：YN482668
| 产品名称: | Tabersonine |
| CAS No.: | 4429-63-4 |
| Chemical Name: | (5α,12R,19α)-2,3,6,7-tetradehydro-aspidospermidine-3-carboxylic acid, methyl ester |
| Synonyms: | 水甘草碱 |
| 分子量: | 336.43 |
| 分子式: | C₂₁H₂₄N₂O₂ |
| SMILES: | O=C(OC)C1=C2NC3=CC=CC=C3[C@@]24CCN5CC=C[C@@]([C@@]45[H])(CC)C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tabersonine 是一种主要从蔷薇中分离出的吲哚类生物碱。Tabersonine 能破坏 Aβ(1-42) 的聚合和改善 Aβ 聚合诱导的细胞毒性。Tabersonine 具有抗炎活性，可用于 ALI/ARDS 的研究。 |
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Kai, T., Zhang, L., Wang, X., et al.Tabersonine inhibits amyloid fibril formation and cytotoxicity of Aβ(1-42)ACS Chem. Neurosci.6(6),879-888(2015)
Qu, Y., Easson, M.L.A.E., Froese, J., et al.Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeastProc. Natl. Acad. Sci. USA112(19),6224-6229(2015)
