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Gardenoside

Cat. No.:YN482688

  • CAS No. :24512-62-7

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    • 生物活性
    • 参考文献
    • 产品名称: Gardenoside
      CAS No.: 24512-62-7
      Chemical Name: 1-(β-D-glucopyranosyloxy)-1S,4aS,7S,7aS-tetrahydro-7-hydroxy-7-(hydroxymethyl)-cyclopenta[c]pyran-4-carboxylic acid, methyl ester
      Synonyms:羟异栀子苷
      分子量:404.37
      分子式:C₁₇H₂₄O₁₁
      SMILES:O=C(C1=CO[C@@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)[C@@]3([H])[C@]1([H])C=C[C@@]3(O)CO)OC
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Gardenoside 是栀子中发现的一种天然化合物,具有保肝作用。Gardenoside 通过调节 P2X3 和 P2X7 受体来抑制慢性缩痛。Gardenoside 对 FFA 诱导的细胞脂肪变性有抑制作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
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      Solvent & Solubility:
    • Ishiguro, K., Yamaki, M., and Takagi, S.Studies on iridoid-related compounds, II. The structure and antimicrobial activity of aglucones of galioside and gardenosideJ. Nat. Prod.46(4),532-536(1983)

      Liang, H., Zhang, L., Wang, H., et al.Inhibitory effect of gardenoside on free fatty acid-induced steatosis in HepG2 hepatocytesInt. J. Mol. Sci.16(11),27749-27756(2015)

      Yu, M., Su, B., and Zhang, X.Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptorsJ. Recept. Signal Transduct. Res.38(3),198-203(2018)

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