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Plumbagin

Cat. No.:YN482693

  • CAS No. :481-42-5

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Plumbagin
      CAS No.: 481-42-5
      Chemical Name: 5-hydroxy-2-methyl-1,4-naphthalenedione
      Synonyms:白花丹素; 2-Methyljuglone
      分子量:188.18
      分子式:C₁₁H₈O₃
      SMILES:O=C1C(C)=CC(C2=C1C=CC=C2O)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Plumbagin (2-Methyljuglone) 是从Plumbago zeylanica L中得到的萘醌类物质,具有抗肿瘤、抗增殖活性。
      IC50和靶点:
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      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Klotz, L.O., Hou, X., and Jacob, C.1,4-Naphthoquinones: From oxidative damage to cellular and inter-cellular signalingMolecules19(9),14902-14918(2014)

      Gupta, S.C., Kim, J.H., Prasad, S., et al.Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticalsCancer Metastasis Rev.29(3),405-434(2010)

      Schramm, A., Matusik, P., Osmenda, G., et al.Targeting NADPH oxidases in vascular pharmacologyVascul. Pharmacol.56(5-6),216-231(2012)

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