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Beta-asarone

Cat. No.:YN482695

  • CAS No. :5273-86-9

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    • 产品名称: Beta-asarone
      CAS No.: 5273-86-9
      Chemical Name: 1,2,4-trimethoxy-5-(1Z)-1-propen-1-yl-benzene
      Synonyms:β-细辛脑
      分子量:208.25
      分子式:C₁₂H₁₆O₃
      SMILES:C/C=C\C1=C(OC)C=C(OC)C(OC)=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Beta-asarone 是石菖蒲中的主要成分,可透过血脑屏障,具有免疫抑制、中枢神经系统抑制、镇静、降温等作用。Beta-asarone 可预防帕金森病。
      IC50和靶点:
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    • Sun, Y.R., Wang, X.Y., Li, S.S., et al.β-Asarone from Acorus gramineus alleviates depression by modulating MKP-1Genet. Mol. Res.14(2),4495-4504(2015)

      Zhang, S., Gui, X.-H., Huang, L.-P., et al.Neuroprotective effects of β-asarone against 6-hydroxy dopamine-induced parkinsonism via JNK/Bcl-2/Beclin-1 PathwayMol. Neurobiol.53(1),83-94(2014)

      Yang, Y.X., Chen, Y.T., Zhou, X.J., et al.Beta-asarone, a major component of Acorus tatarinowii Schott, attenuates focal cerebral ischemia induced by middle cerebral artery occlusion in ratsBMC Complement. Altern. Med.13,(2013)

      Wei, G., Chen, Y.B., Chen, D.F., et al.β-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and AβPP/PS1 miceJ. Alzheimers Dis.33(3),863-880(2013)

      Zou, X., Liu, S.L., Zhou, J.Y., et al.β-Asarone induces LoVo colon cancer cell apoptosis by up-regulation of caspases through a mitochondrial pathway in vitro and in vivoAsian Pac. J. Cancer Prev.13(10),5291-5298(2012)

      Rajput, S.B., and Karuppayil, S.M.β-Asarone, an active principle of Acorus calamus rhizome, inhibits morphogenesis, biofilm formation and ergosterol biosynthesis in Candida albicansPhytomedicine20(2),139-142(2013)

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