Ganodermanontriol
Cat. No.：YN482698
CAS No. ：106518-63-2
| 产品名称: | Ganodermanontriol |
| CAS No.: | 106518-63-2 |
| Chemical Name: | 24S,25R,26-trihydroxy-lanosta-7,9(11)-dien-3-one |
| Synonyms: | |
| 分子量: | 472.70 |
| 分子式: | C₃₀H₄₈O₄ |
| SMILES: | CC1(C)C(CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC[C@H](O)[C@](C)(O)CO)CC[C@](C)4C3=CC[C@@]12[H])=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ganodermanontriol，是从Ganoderma lucidum中提取的一种甾醇，通过 HO-1 的表达诱导 t-BHP 损伤肝细胞的抗炎活性。Ganodermanontriol 具有保肝作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Min, B.-S., Nakamura, N., Miyashiro, H., et al.Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 proteaseChem. Pharm. Bull.46(10),1607-1612(1998)
Liu, J., Kurashiki, K., Shimizu, K., et al.Structure–activity relationship for inhibition of 5α-reductase by triterpenoids isolated from Ganoderma lucidumBioorg. Med. Chem.14(24),8654-8660(2006)
Jiang, J., Jedinak, A., and Silva, D.Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPABiochem. Biophys. Res. Commun.415(2),325-329(2011)
Hu, Z., Du, R., Xiu, L., et al.Protective effect of triterpenes of Ganoderma lucidum on lipopolysaccharide-induced inflammatory responses and acute liver injuryCytokine127,154917(2020)
