Ganoderic acid H
Cat. No.：YN482701
| 产品名称: | Ganoderic acid H |
| CAS No.: | 98665-19-1 |
| Chemical Name: | 12β-(acetyloxy)-3β-hydroxy-7,11,15,23-tetraoxo-lanost-8-en-26-oic acid |
| Synonyms: | |
| 分子量: | 572.69 |
| 分子式: | C₃₂H₄₄O₉ |
| SMILES: | CC(C)(C1C2)C(O)CCC1(C)C3=C(C4(C(CC(C4(C(OC(C)=O)C3=O)C)C(C)CC(CC(C)C(O)=O)=O)=O)C)C2=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ganoderic acid H 是一种从灵芝中提取的羊毛脂烷型三萜，能通过抑制转录因子AP-1 和 NF-kappaB 信号来抑制乳腺癌细胞细胞的生长和入侵。 |
| IC50和靶点: | |
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Morigiwa, A., Kitabatake, K., Fujimoto, Y., et al.Angiotensin converting enzyme-inhibitory triterpenes from Ganoderma lucidumChem. Pharm. Bull. (Tokyo)34(7),3025-3028(1986)
El-Mekkawy, S., Meselhy, M.R., Nakamura, N., et al.Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidumPhytochemistry49(6),1651-1657(1998)
Jiang, J., Grieb, B., Thyagarajan, A., et al.Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-κB signalingInt. J. Mol. Med.21(5),577-584(2008)
Koyama, K., Imaizumi, T., Akiba, M., et al.Antinociceptive components of Ganoderma lucidumPlanta Med.63(3),224-227(1997)
