3,5,6,7,8,3',4'-Heptemthoxyflavone
Cat. No.：YN482756
| 产品名称: | 3,5,6,7,8,3',4'-Heptemthoxyflavone |
| CAS No.: | 1178-24-1 |
| Chemical Name: | 2-(3,4-dimethoxyphenyl)-3,5,6,7,8-pentamethoxy-H-1-benzopyran-4-one |
| Synonyms: | 3,5,6,7,8,3',4'-七甲氧基黄酮,3,3',4',5,6,7,8-heptamethoxyflavone |
| 分子量: | 432.42 |
| 分子式: | C₂₂H₂₄O₉ |
| SMILES: | O=C1C(OC)=C(C2=CC=C(OC)C(OC)=C2)OC3=C(OC)C(OC)=C(OC)C(OC)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 3,5,6,7,8,3',4'-Heptemthoxyflavone 是一种蜜柑皮中的黄酮，具有抗肿瘤起始活性和抗神经炎症活性。3,5,6,7,8,3',4'-Heptemthoxyflavone 能抑制胶原酶的活性，增加人真皮成纤维细胞新生 (HDFn) 细胞中 I 型前胶原的含量。3,5,6,7,8,3',4'-Heptemthoxyflavone 能通过 cAMP/ERK/CREB 信号诱导脑源性神经营养因子(BDNF) 表达，降低 C6 细胞磷酸二酯酶活性。 |
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Pick, A., Müller, H., Mayer, R., et al.Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP)Bioorg. Med. Chem.19(6),2090-2102(2011)
Kim, H.-I., Jeong, Y.-U., Kim, J.-H., et al.3,5,6,7,8,3',4'-heptamethoxyflavone, a Citrus flavonoid, inhibits collagenase activity and induces type I procollagen synthesis in HDFn cellsInt. J. Mol. Sci.19(2),620(2018)
Kawaii, S., Tomono, Y., Katase, E., et al.Antiproliferative activity of flavonoids on several cancer cell linesBiosci. Biotechnol. Biochem.63(5),896-899(1999)
Sawamoto, A., Okuyama, S., Yamamoto, K., et al.3,5,6,7,8,3',4'-heptamethoxyflavone, a citrus flavonoid, ameliorates corticosterone-Induced depression-like behavior and restores brain-derived neurotrophic factor expression, neurogenesis, and neuroplasticity in the hippocampusMolecules21(4),541(2016)
