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(20R)-Protopanaxadiol

Cat. No.:YN482758

  • CAS No. :7755-01-3

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    • 生物活性
    • 参考文献
    • 产品名称: (20R)-Protopanaxadiol
      CAS No.: 7755-01-3
      Chemical Name: dammar-24-ene-3β,12β,20R-triol
      Synonyms:(20R)-Protopanaxdiol,20R-Protopanaxadiol,Protopanaxadiol,(20R)-原人参二醇
      分子量:460.73
      分子式:C₃₀H₅₂O₃
      SMILES:C[C@]([C@@](C[C@H]1O)([H])[C@]2(CC[C@@H]3O)C)(CC[C@@]2([H])C3(C)C)[C@]4([C@@]1([H])[C@]([C@](C)(O)CC/C=C(C)/C)([H])CC4)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: (20R)-Protopanaxadiol 是黑参中 20(R)-ginsenoside Rg3 的三萜皂苷代谢物。(20R)-Protopanaxadiol 具有抗肿瘤活性和细胞毒性,能有效抑制幽门螺杆菌的生长。
      IC50和靶点:
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    • Nam-In, B., Kim, D.S., Lee, Y.H., et al.Cytotoxicities of ginseng saponins and their degradation products against some cancer cell linesArch. Pharm. Res.18(3),164-168(1995)

      Hasegawa, H., Matsumiya, S., Uchiyama, M., et al.Inhibitory effect of some triterpenoid saponins on glucose transport in tumor cells and its application to in vitro cytotoxic and antiviral activitiesPlanta Med.60(3),240-243(1994)

      Bae, E.A., Han, M.J., Choo, M.K., et al.Metabolism of 20(S)- and 20(R)-ginsenoside Rg3 by human intestinal bacteria and its relation to in vitro biological activitiesBiol. Pharm. Bull.25(1),58-63(2002)

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