Steviol
Cat. No.：YN482765
| 产品名称: | Steviol |
| CAS No.: | 471-80-7 |
| Chemical Name: | (4α)-13-hydroxy-kaur-16-en-18-oic acid |
| Synonyms: | 甜菊醇 |
| 分子量: | 318.45 |
| 分子式: | C₂₀H₃₀O₃ |
| SMILES: | C[C@@]1(C(O)=O)CCC[C@@]2(C)[C@@]3([H])[C@@]4(CC([C@@](CC3)(O)C4)=C)CC[C@]12[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Steviol 是甜菊糖甙的主要代谢物。Steviol 通过降低 AQP2 的表达和促进 AQP2 的降解以减缓肾囊肿的生长。 |
| IC50和靶点: | |
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Srimaroeng, C., Jutabha, P., Pritchard, J.B., et al.Interactions of stevioside and steviol with renal organic anion transporters in S2 cells and mouse renal cortical slicesPharm Res.22(6),858-866(2005)
Brusick, D.J.A critical review of the genetic toxicity of steviol and steviol glycosidesFood Chem. Toxicol.46(Suppl 7),S83-S91(2008)
Roberts, A., and Renwick, A.G.Comparative toxicokinetics and metabolism of rebaudioside A, stevioside, and steviol in ratsFood Chem. Toxicol.46(Suppl 7),S31-S39(2008)
