7-Ethylcamptothecin
Cat. No.：YN482781
CAS No. ：78287-27-1
| 产品名称: | 7-Ethylcamptothecin |
| CAS No.: | 78287-27-1 |
| Chemical Name: | (4S)-4,11-diethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| Synonyms: | 7-乙基喜树碱 |
| 分子量: | 376.41 |
| 分子式: | C₂₂H₂₀N₂O₄ |
| SMILES: | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC=CC=C5N=C4C3=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 7-Ethylcamptothecin 是喜树碱类似物之一。 喜树碱 (CPT) 是一种从喜树 (camptothecin analogues) 中分离出的细胞毒性生物碱，对 L1210 白血病和 Walker 256 癌肉瘤模型具有很强的抗肿瘤活性。 |
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Yoshikawa, M., Ikegami, Y., Hayasaka, S., et al.Novel camptothecin analogues that circumvent ABCG2-associated drug resistance in human tumor cellsInt. J. Cancer110(6),921-927(2004)
Kunimoto, T., Nitta, K., Tanaka, T., et al.Antitumor activity of a new camptothecin derivative, SN-22, against various murine tumorsJ. Pharmacobiodyn.10(3),148-151(1987)
