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7,4'-Di-O-methylapigenin

Cat. No.:YN482794

  • CAS No. :5128-44-9

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: 7,4'-Di-O-methylapigenin
      CAS No.: 5128-44-9
      Chemical Name: 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
      Synonyms:4',7-Dimethoxy-5-Hydroxyflavone
      分子量:298.29
      分子式:C₁₇H₁₄O₅
      SMILES:O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(OC)=CC(O)=C13
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 7,4 '-Di-O-methylapigenin可能具有抗真菌c.zeyheri的活性,是一种潜在的抗真菌药物。除此之外,该化合物还能抑制药物流出泵(IC50 = 51.64μg /毫升)。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Chaurasiya, N.D., Zhao, J., Pandey, P., et al.Selective inhibition of human monoamine oxidase B by acacetin 7-methyl ether isolated from Turnera diffusa (damiana)Molecules24(4),810(2019)

      Goettert, M., Schattel, V., Koch, P., et al.Biological evaluation and structural determinants of p38α mitogen-activated-protein kinase and c-Jun-N-terminal kinase 3 inhibition by flavonoidsChembiochem11(18),(2010)

      Tewtrakul, S., and Subhadhirasakul, S.Effects of compounds from Kaempferia parviflora on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha productions in RAW264.7 macrophage cellsJ. Ethnopharmacol.120(1),81-84(2008)

      Mangoyi, R., Midiwo, J., and Mukanganyama, S.Isolation and characterization of an antifungal compound 5-hydroxy-7,4’-dimethoxyflavone from Combretum zeyheriBMC Complement. Altern. Med.15,405(2015)

      Fourie, R.G., and Snyckers, F.O.A flavone with antiinflammatory activity from the roots of Rhus undulataJ. Nat. Prod.47(6),1057-1058(1984)

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