Cytosporone B
Cat. No.：YN482796
CAS No. ：321661-62-5
| 产品名称: | Cytosporone B |
| CAS No.: | 321661-62-5 |
| Chemical Name: | 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetic acid, ethyl ester |
| Synonyms: | Csn-B; Dothiorelone G |
| 分子量: | 322.40 |
| 分子式: | C₁₈H₂₆O₅ |
| SMILES: | O=C(OCC)CC1=CC(O)=CC(O)=C1C(CCCCCCC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cytosporone B (Csn-B; Dothiorelone G) 是天然存在的核孤儿受体Nur77/NR4A1激动剂，EC50值为0.278 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Zhan, Y., Du, X., Chen, H., et al.Cytosporone B is an agonist for nuclear orphan receptor Nur77Nat. Chem. Biol.4,548-556(2008)
Hu, Y.W., Zhang, P., Yang, J.Y., et al.Nur77 decreases atherosclerosis progression in apoE-/- mice fed a high-fat/high-cholesterol dietPLoS One9(1),1-12(2014)
Dai, Y., Zhang, W., Sun, Q., et al.Nuclear receptor nur77 promotes cerebral cell apoptosis and induces early brain injury after experimental subarachnoid hemorrhage in ratsJ. Neurosci. Res.92,1110-1121(2015)
Beau, J., Mahid, N., Burda, W.N., et al.Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persooniiMar. Drugs10(4),762-774(2012)
Li, J., Lv, C., Sun, W., et al.Cytosporone B, an inhibitor of the type III secretion system of Salmonella enterica serovar TyphimuriumAntimicrob. Agents Chemother.57(5),2191-2198(2013)
