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Nootkatone

Cat. No.:YN482829

  • CAS No. :4674-50-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Nootkatone
      CAS No.: 4674-50-4
      Chemical Name: (4R,4aS,6R)-4,4a,5,6,7,8-hexahydro-4,4a-dimethyl-6-(1-methylethenyl)-2(3H)-naphthalenone
      Synonyms:诺卡酮; (+)
      分子量:218.33
      分子式:C₁₅H₂₂O
      SMILES:O=C1C=C2CC[C@@H](C(C)=C)C[C@@]2(C)[C@H](C)C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Nootkatone,来自于Alpiniae OxyphyllaeFructus 的神经保护剂,具有抗氧化和抗炎作用。Nootkatone 可改善脂多糖诱导的阿尔茨海默氏病小鼠模型的认知障碍。
      IC50和靶点:
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    • MacLeod, W.D., Jr., and Buigues, N.M.Sesquiterpenes. I. Nootkatone, A new grapefruit flavor constituentJ. Food Sci.29(5),565 - 568(2006)

      Panella, N.A., Dolan, M.C., Karchesy, J.J., et al.Use of novel compounds for pest control: Insecticidal and acaricidal activity of essential oil components from heartwood of Alaska yellow cedarJ. Med. Entomol.42(3),352-358(2005)

      Maistrello, L., Henderson, G., and Laine, R.A.Comparative effects of vetiver oil, nootkatone and disodium octaborate tetrahydrate on Coptotermes formosanus and its symbiotic faunaPest. Manag. Sci.59(1),58-68(2003)

      Murase, T., Misawa, K., Haramizu, S., et al.Nootkatone, a characteristic constituent of grapefruit, stimulates energy metabolism and prevents diet-induced obesity by activating AMPKAm. J. Physiol. Endocrinol. Metab.299(2),E266-E275(2010)

      Seo, E.J., Lee, D.-U., Kwak, J.H., et al.Antiplatelet effects of Cyperus rotundus and its component (+)-nootkatoneJ. Ethnopharmacol.135(1),48-54(2011)

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