Hirsuteine
Cat. No.：YN482831
| 产品名称: | Hirsuteine |
| CAS No.: | 35467-43-7 |
| Chemical Name: | (αE,2S,3R,12bR)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic acid, methyl ester |
| Synonyms: | 去氢毛钩藤碱 |
| 分子量: | 366.45 |
| 分子式: | C₂₂H₂₆N₂O₃ |
| SMILES: | O=C(OC)/C([C@H]([C@H](CN1CC2)C=C)C[C@]1([H])C3=C2C(C=CC=C4)=C4N3)=C/OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hirsuteine 是一种从钩藤属植物中提取的吲哚生物碱。Hirsuteine 通过阻断离子渗透通过烟碱受体通道复合物，非竞争性地拮抗烟碱介导的多巴胺释放。 |
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Shimada, Y., Goto, H., Itoh, T., et al.Evaluation of the protective effects of alkaloids isolated from the hooks and stems of Uncaria sinensis on glutamate-induced neuronal death in cultured cerebellar granule cells from ratsJ. Pharm. Pharmacol.51(6),715-722(1999)
Watano, T., Nakazawa, K., Obama, T., et al.Non-competitive antagonism by hirsuteine of nicotinic receptor-mediated dopamine release from rat pheochromocytoma cellsJpn. J. Pharmacol.61(4),351-356(1993)
