4'-Demethylpodophyllotoxin
Cat. No.：YN482891
CAS No. ：40505-27-9
| 产品名称: | 4'-Demethylpodophyllotoxin |
| CAS No.: | 40505-27-9 |
| Chemical Name: | (5R,5aR,8aR,9R)-5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3′,4′:6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one |
| Synonyms: | 4'-去甲基鬼臼毒素 |
| 分子量: | 400.38 |
| 分子式: | C₂₁H₂₀O₈ |
| SMILES: | O=C1[C@]2([H])[C@H](C3=CC(OC)=C(O)C(OC)=C3)C(C=C(OCO4)C4=C5)=C5[C@H](O)[C@@]2([H])CO1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 4'-Demethylpodophyllotoxin 是Podophyllum hexandrum根和P. peltatum中含有的一种木脂素类化合物。4'-Demethylpodophyllotoxin 对多种癌细胞系具有潜在的细胞毒性。 |
| IC50和靶点: | |
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Loike, J.D., Brewer, C.F., Sternlicht, H., et al.Structure-activity study of the inhibition of microtubule assembly in vitro by podophyllotoxin and its congenersCancer Res.38(9),2688-2693(1978)
Jiang, R.-W., Zhou, J.-R., Hon, P.-M., et al.Lignans from Dysosma versipellis with inhibitory effects on prostate cancer cell linesJ. Nat. Prod.70(2),283-286(2007)
