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Isocorydine

Cat. No.:YN482963

  • CAS No. :475-67-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Isocorydine
      CAS No.: 475-67-2
      Chemical Name: (6aS)-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol
      Synonyms:Luteanin,Uzokoridin,异紫堇定,S-Isocorydine(+),(+)-Isocorynoline,Artabotrin
      分子量:341.40
      分子式:C₂₀H₂₃NO₄
      SMILES:COC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C24
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Isocorydine 是从美德罗克线虫Dicranostigma leptopodum (Maxim.) Fedde中分离出来的。Isocorydine 与阿霉素 (DOX) 的结合具有消除肝细胞癌 (HCC) 的潜力。
      IC50和靶点:
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      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Bhakuni, D.S., Tewari, S., and Dhar, M.M.Aporphine alkaloids of Annona squamosaPhytochemistry11(5),1819-1822(1972)

      Zhao, Y.-Q., Li, G.-R., Zhang, D.-Z., et al.Effects of isocorydine on action potentials in isolated canine purkinje fibers and ventricular musclesJ. Mol. Cell. Cardiol.12(4),324-327(1991)

      Jiang, Q.-S., Huang, X.-N., Sun, A.-S., et al.Relation of vasodilative action of isocorydine to cyclic nucleotidesChi. J. Pharm. Toxicol.15(4),251-255(2011)

      Zhong, M., Liu, Y., Liu, J., et al.Isocorydine derivatives and their anticancer activitiesMolecules19(8),12099-12115(2014)

      Pan, J.-X., Chen, G., Li, J.-J., et al.Isocorydine suppresses doxorubicin-induced epithelial-mesenchymal transition via inhibition of ERK signaling pathways in hepatocellular carcinomaAm. J. Cancer Res.8(1),154-164(2018)

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