Isocorydine
Cat. No.:YN482963
CAS No. :475-67-2
产品名称: | Isocorydine |
CAS No.: | 475-67-2 |
Chemical Name: | (6aS)-5,6,6a,7-tetrahydro-1,2,10-trimethoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol |
Synonyms: | Luteanin,Uzokoridin,异紫堇定,S-Isocorydine(+),(+)-Isocorynoline,Artabotrin |
分子量: | 341.40 |
分子式: | C₂₀H₂₃NO₄ |
SMILES: | COC1=C2C3=C(C=C1OC)CCN(C)[C@@]3([H])CC4=CC=C(OC)C(O)=C24 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Isocorydine 是从美德罗克线虫Dicranostigma leptopodum (Maxim.) Fedde中分离出来的。Isocorydine 与阿霉素 (DOX) 的结合具有消除肝细胞癌 (HCC) 的潜力。 |
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Bhakuni, D.S., Tewari, S., and Dhar, M.M.Aporphine alkaloids of Annona squamosaPhytochemistry11(5),1819-1822(1972)
Zhao, Y.-Q., Li, G.-R., Zhang, D.-Z., et al.Effects of isocorydine on action potentials in isolated canine purkinje fibers and ventricular musclesJ. Mol. Cell. Cardiol.12(4),324-327(1991)
Jiang, Q.-S., Huang, X.-N., Sun, A.-S., et al.Relation of vasodilative action of isocorydine to cyclic nucleotidesChi. J. Pharm. Toxicol.15(4),251-255(2011)
Zhong, M., Liu, Y., Liu, J., et al.Isocorydine derivatives and their anticancer activitiesMolecules19(8),12099-12115(2014)
Pan, J.-X., Chen, G., Li, J.-J., et al.Isocorydine suppresses doxorubicin-induced epithelial-mesenchymal transition via inhibition of ERK signaling pathways in hepatocellular carcinomaAm. J. Cancer Res.8(1),154-164(2018)