Neotuberostemonine
Cat. No.：YN483027
| 产品名称: | Neotuberostemonine |
| CAS No.: | 143120-46-1 |
| Chemical Name: | (2S,7aR,8R,8aR,11S,11aR,11bS,11cR)-8-ethyldodecahydro-11-methyl-2-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-furo[2,3-h]pyrrolo[3,2,1-jk][1]benzazepin-10(2H)-one |
| Synonyms: | 新对叶百部碱 |
| 分子量: | 375.50 |
| 分子式: | C₂₂H₃₃NO₄ |
| SMILES: | CC[C@@H]1[C@]2([H])[C@]3([H])[C@](C[C@]([C@](O4)([H])C[C@H](C)C4=O)([H])N3CCCC2)([H])[C@@]([C@@H]5C)([H])[C@]1([H])OC5=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Neotuberostemonine，是结核分枝杆菌根中主要的止咳生物碱之一，通过抑制巨噬细胞的募集和活化来减轻博来霉素 (Bleomycin, HY-17565A) 诱导的肺纤维化。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Xiang, J., Cheng, S., Feng, T., et al.Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophagesInt. Immunopharmacol.36,158-164(2016)
Yun, J., Lee, K.Y., and Park, B.Neotuberostemonine inhibits osteoclastogenesis via blockade of NF-kB pathwayBiochimie157,81-91(2019)
Chung, H.-S., Hon, P.-M., Lin, G., et al.Antitussive activity of Stemona alkaloids from Stemona tuberosaPlanta Med.69(10),914-920(2003)
