Mulberrin
Cat. No.:YN483046
CAS No. :62949-79-5
产品名称: | Mulberrin |
CAS No.: | 62949-79-5 |
Chemical Name: | 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-bis(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one |
Synonyms: | 桑黄酮; Kuwanon C |
分子量: | 422.47 |
分子式: | C₂₅H₂₆O₆ |
SMILES: | C/C(C)=C\CC1=C2C(C(C(C/C=C(C)\C)=C(C3=C(C=C(O)C=C3)O)O2)=O)=C(O)C=C1O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Mulberrin 有效抑制有机阴离子转运多肽 2B1 (OATP2B1) 介导的雌酮-3-硫酸盐 (E3S) 摄取,IC50值为 1.8±1.5 μM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Nomura, T., Fukai, T., and Katayanagi, M.Kuwanon A, B, C and oxydihydromorusin, four new flavones from the root bark of the cultivated mulberry tree (Morus alba L.)Chem. Pharm. Bull.25(3),529-532(1977)
Mazimba, O., Majinda, R.R.T., and Motlhanka, D.Antioxidant and antibacterial constituents from Morus nigraAfr. J. Pharma. Pharmaco.5(6),751-754(2011)
Sohn, H.-Y., Son, K.H., Kwon, C.-S., et al.Antimicrobial and cytotoxic activity of 18 prenylated flavonoids isolated from medicinal plants: Morus alba L., Morus mongolica Schneider, Broussnetia papyrifera (L.) Vent, Sophora flavescens Ait and Echinosophora koreensis NakaiPhytomedicine11(7-8),666-672(2004)
Ferlinahayati, Syah, Y.M., Juliawaty, L.D., et al.Phenolic constituents from the wood of Morus australis with cytotoxic activityZ. Naturforsch. C. J. Biosci.63(1-2),35-39(2008)
Cao, W., Dong, Y., Zhao, W., et al.Mulberrin attenuates 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP)-induced Parkinson's disease by promoting Wnt/β-catenin signaling pathwayJ. Chem. Neuroanat.98,63-70(2019)