Heraclenin
Cat. No.:YN483075
产品名称: | Heraclenin |
CAS No.: | 2880-49-1 |
Chemical Name: | 9-[[(2R)-3,3-Dimethyl-2-oxiranyl]methoxy]-7H-furo[3,2-g][1]benzopyran-7-one; (+)-Heraclenin; Prangenin; 9-[[(2R)-3,3-Dimethyloxiranyl]methoxy]-7H-furo[3,2-g][1]benzopyran-7-one; (R)-(+)-9-(2,3-Epoxy-3-methylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-one |
Synonyms: | 独活内酯 |
分子量: | 286.28 |
分子式: | C₁₆H₁₄O₅ |
SMILES: | CC1(C)[C@H](O1)COC2=C(OC=C3)C3=CC(C=C4)=C2OC4=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Heraclenin,是一种天然呋喃香豆素,可从Prangos pabularia根部分离出来。Heraclenin 通过靶向激活的 T 细胞核因子 (NFAT) 来抑制人原代 T 细胞中 T 细胞受体介导的增殖,这种作用存在浓度依赖性。 |
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1. Schimmer, O., et al., . Mutagenicity of a furocoumarin epoxide, heraclenin, in Chlamydomonas reinhardii. Mutation research. 169(1-2): 47-50. PMID: 39452362. Abel, G., et al., . Chromosome-damaging effects of heraclenin in human lymphocytes in vitro. Mutation research. 169(1-2): 51-4. PMID: 39452373. Mishra, K C., et al., 1969. Anticoagulant activity of Heraclenin. Indian journal of physiology and pharmacology. 13(3): 153-5. PMID: 53626304. Appendino, Giovanni., et al., 2004. Coumarins from Opopanax chironium. New dihydrofuranocoumarins and differential induction of apoptosis by imperatorin and heraclenin. Journal of natural products. 67(4): 532-6. PMID: 15104479