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5,7-Dihydroxy-4-methylcoumarin

Cat. No.:YN483094

  • CAS No. :2107-76-8

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    • 生物活性
    • 参考文献
    • 产品名称: 5,7-Dihydroxy-4-methylcoumarin
      CAS No.: 2107-76-8
      Chemical Name: 5,7-dihydroxy-4-methyl-2H-1-benzopyran-2-one
      Synonyms:5,7-二羟基-4-甲基香豆素,Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin
      分子量:192.17
      分子式:C₁₀H₈O₄
      SMILES:O=C1C=C(C)C2=C(O)C=C(O)C=C2O1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 5,7-Dihydroxy-4-methylcoumarin 是墨西哥龙蒿中的一种香豆素衍生物。
      IC50和靶点:
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    • Hoult, J.R.S., and Payá, M.Pharmacological and biochemical actions of simple coumarins: Natural products with therapeutic potentialGen. Pharmacol.27(4),713-722(1996)

      Kabeya, L.M., Fuzissaki, C.N., Andrade, M.F., et al.4-methylcoumarin derivatives inhibit human neutrophil oxidative metabolism and elastase activityJ. Med. Food16(8),692-700(2013)

      Brubaker, A.N., DeRuiter, J., and Whitmer, W.L.Synthesis and rat lens aldose reductase inhibitory activity of some benzopyran-2-onesJ. Med. Chem.29(6),1094-1099(1986)

      Sharma, A., Tiwari, M.N., and Supuran, C.T.Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IXJ. Enzyme Inhib. Med. Chem.29(2),292-296(2014)

      Nichols, D.B., Leão, R.A.C., Basu, A., et al.Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitorsChem. Biol. Drug Des.81(5),607-614(2013)

      Macáková, K., Řeháková, Z., Mladěnka, P., et al.In vitro platelet antiaggregatory properties of 4-methylcoumarinsBiochimie94(12),2681-2686(2012)

      Jadhav, S.G., Meshram, R.J., Gond, D.S., et al.Inhibition of growth of Helicobacter pylori and its urease by coumarin derivatives: Molecular docking analysisJ. Pharm. Res.7(8),705-711(2013)

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