5,7-Dihydroxy-4-methylcoumarin
Cat. No.:YN483094
产品名称: | 5,7-Dihydroxy-4-methylcoumarin |
CAS No.: | 2107-76-8 |
Chemical Name: | 5,7-dihydroxy-4-methyl-2H-1-benzopyran-2-one |
Synonyms: | 5,7-二羟基-4-甲基香豆素,Methyl-2H-Chromen-2-One,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin |
分子量: | 192.17 |
分子式: | C₁₀H₈O₄ |
SMILES: | O=C1C=C(C)C2=C(O)C=C(O)C=C2O1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 5,7-Dihydroxy-4-methylcoumarin 是墨西哥龙蒿中的一种香豆素衍生物。 |
IC50和靶点: | |
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Hoult, J.R.S., and Payá, M.Pharmacological and biochemical actions of simple coumarins: Natural products with therapeutic potentialGen. Pharmacol.27(4),713-722(1996)
Kabeya, L.M., Fuzissaki, C.N., Andrade, M.F., et al.4-methylcoumarin derivatives inhibit human neutrophil oxidative metabolism and elastase activityJ. Med. Food16(8),692-700(2013)
Brubaker, A.N., DeRuiter, J., and Whitmer, W.L.Synthesis and rat lens aldose reductase inhibitory activity of some benzopyran-2-onesJ. Med. Chem.29(6),1094-1099(1986)
Sharma, A., Tiwari, M.N., and Supuran, C.T.Novel coumarins and benzocoumarins acting as isoform-selective inhibitors against the tumor-associated carbonic anhydrase IXJ. Enzyme Inhib. Med. Chem.29(2),292-296(2014)
Nichols, D.B., Leão, R.A.C., Basu, A., et al.Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitorsChem. Biol. Drug Des.81(5),607-614(2013)
Macáková, K., Řeháková, Z., Mladěnka, P., et al.In vitro platelet antiaggregatory properties of 4-methylcoumarinsBiochimie94(12),2681-2686(2012)
Jadhav, S.G., Meshram, R.J., Gond, D.S., et al.Inhibition of growth of Helicobacter pylori and its urease by coumarin derivatives: Molecular docking analysisJ. Pharm. Res.7(8),705-711(2013)