Syrosingopine
Cat. No.：YN483099
| 产品名称: | Syrosingopine |
| CAS No.: | 84-36-6 |
| Chemical Name: | (3β,16β,17α,18β,20α)-18-[[4-[(ethoxycarbonyl)oxy]-3,5-dimethoxybenzoyl]oxy]-11,17-dimethoxy-yohimban-16-carboxylic acid, methyl ester |
| Synonyms: | Su 3118 |
| 分子量: | 666.71 |
| 分子式: | C₃₅H₄₂N₂O₁₁ |
| SMILES: | [H][C@@]12C(NC3=C4C=CC(OC)=C3)=C4CCN1C[C@]5(C[C@@H](OC(C6=CC(OC)=C(OC(OCC)=O)C(OC)=C6)=O)[C@H](OC)[C@@H](C(OC)=O)[C@]5(C2)[H])[H] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Syrosingopine (Su 3118) 是一种抗高血压药物。Syrosingopine 能降低多巴胺的水平。 |
| IC50和靶点: | |
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Benjamin, D., Robay, D., Hindupur, S.K., et al.Dual inhibition of the lactate transporters MCT1 and MCT4 is synthetic lethal with metformin due to NAD+ depletion in cancer cellsCell Rep.25(11),3047-3058(2018)
Benjamin, D., Colombi, M., Hindupur, S.K., et al.Syrosingopine sensitizes cancer cells to killing by metforminSci. Adv.2(12),e1601756(2016)
Orlans, F.B., Finger, K.F., and Brodie, B.B.Pharmacological consequences of the selective release of peripheral norepinephrine by syrosingopine (Su 3118)J. Pharmacol. Exp. Ther.128,131-139(1960)
