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Tormentic acid

Cat. No.:YN483112

  • CAS No. :13850-16-3

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    • 生物活性
    • 参考文献
    • 产品名称: Tormentic acid
      CAS No.: 13850-16-3
      Chemical Name: (2α,3β)-2,3,19-trihydroxy-urs-12-en-28-oic acid
      Synonyms:2Α,19Α-二羟基熊果酸
      分子量:488.70
      分子式:C₃₀H₄₈O₅
      SMILES:OC([C@]12[C@]([C@](O)([C@H](C)CC2)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@@H](O)[C@H](O)C4)C)([H])CC5)C)([H])[C@]5(C)[C@]3(C)CC1)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Tormentic acid 是从Rosa rugosa中分离出来的一种三萜,具有抗炎、降血脂和抗动脉粥样硬化的作用。
      IC50和靶点:
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    • Banno, N., Akihisa, T., Tokuda, H., et al.Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effectsBiosci. Biotechnol. Biochem.68(1),85-90(2004)

      Wang, Y.-L., Sun, G.-Y., Zhang, Y., et al.Tormentic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NF-κB signaling pathwayMol. Med. Rep.14(4),3559-3564(2016)

      Wu, J.-B., Kuo, Y.-H., Lin, C.-H., et al.Tormentic acid, a major component of suspension cells of Eriobotrya japonica, suppresses high-fat diet-induced diabetes and hyperlipidemia by glucose transporter 4 and AMP-activated protein kinase phosphorylationJ. Agric. Food Chem.62(44),10717-10726(2014)

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