Tormentic acid
Cat. No.:YN483112
产品名称: | Tormentic acid |
CAS No.: | 13850-16-3 |
Chemical Name: | (2α,3β)-2,3,19-trihydroxy-urs-12-en-28-oic acid |
Synonyms: | 2Α,19Α-二羟基熊果酸 |
分子量: | 488.70 |
分子式: | C₃₀H₄₈O₅ |
SMILES: | OC([C@]12[C@]([C@](O)([C@H](C)CC2)C)([H])C3=CC[C@@]([C@@]4([C@@](C(C)([C@@H](O)[C@H](O)C4)C)([H])CC5)C)([H])[C@]5(C)[C@]3(C)CC1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Tormentic acid 是从Rosa rugosa中分离出来的一种三萜,具有抗炎、降血脂和抗动脉粥样硬化的作用。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Banno, N., Akihisa, T., Tokuda, H., et al.Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effectsBiosci. Biotechnol. Biochem.68(1),85-90(2004)
Wang, Y.-L., Sun, G.-Y., Zhang, Y., et al.Tormentic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NF-κB signaling pathwayMol. Med. Rep.14(4),3559-3564(2016)
Wu, J.-B., Kuo, Y.-H., Lin, C.-H., et al.Tormentic acid, a major component of suspension cells of Eriobotrya japonica, suppresses high-fat diet-induced diabetes and hyperlipidemia by glucose transporter 4 and AMP-activated protein kinase phosphorylationJ. Agric. Food Chem.62(44),10717-10726(2014)