Galgravin
Cat. No.：YN483217
| 产品名称: | Galgravin |
| CAS No.: | 528-63-2 |
| Chemical Name: | (2R,3R,4S,5S)-rel-2,5-bis(3,4-dimethoxyphenyl)tetrahydro-3,4-dimethyl-furan |
| Synonyms: | 盖尔格拉文 |
| 分子量: | 372.45 |
| 分子式: | C₂₂H₂₈O₅ |
| SMILES: | C[C@H]1[C@@H](C)[C@H](C2=CC=C(OC)C(OC)=C2)O[C@@H]1C3=CC=C(OC)C(OC)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Galgravin 是Nectandra megapotamica中的一种活性化合物，具有抗炎作用。Galgravin 具有体外细胞毒活性，能诱导白血病细胞凋亡。 |
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Biftu, T., Gamble, N.F., Doebber, T., et al.Conformation and activity of tetrahydrofuran lignans and analogues as specific platelet activating factor antagonistsJ. Med. Chem.29(10),1917-1921(1986)
Asai, M., Lee, J.-W., Itakura, Y., et al.Effects of veraguensin and galgravin on osteoclast differentiation and functionCytotechnology64(3),315-322(2012)
Zhai, H., Inoue, T., Moriyama, M., et al.Neuroprotective effects of 2,5-diaryl-3,4-dimethyltetrahydrofuran neolignansBiol. Pharm. Bull.28(2),289-293(2005)
da Silva Filho, A.A., Andrade e Silva, M.L., Carvalho, J.C.T., et al.Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and ratsJ. Pharm. Pharmacol.56(9),1179-1184(2004)
